left main coronary artery aneurysm

aneurysms of the left main coronary artery are exceedingly rare clinical entities, encountered incidentally in approximately 0.1% of patients who undergo routine angiography. the most common cause of coronary artery aneurysms is atherosclerosis. angiography is the gold standard for diagnosis and treatment. depending on the severity of the coexisting coronary stenosis, patients with left main coronary artery aneurysms can be effectively managed either surgically or pharmacologically. we herein report a case of left main coronary artery aneurysm in a 72-year-old man with a prior history of hypertension presenting to our hospital because of unstable angina. the electrocardiogram showed st-segment depression and t-wave inversion in the precordial leads. all the data of blood chemistry were normal. echocardiography showed akinetic anterior wall, septum, and apex, mild mitral regurgitation and ejection fraction of 45%. coronary angiography revealed a saccular aneurysm of the left main coronary artery with significant stenosis in the left anterior descending, left circumflex, and right coronary artery. the patient immediately underwent coronary artery bypass grafting and ligation of the aneurysm. at six months’ follow-up, he remained asymptomatic.